Class Notes (1,100,000)
CA (620,000)
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BIOB34H3 (300)
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Lecture

BIOB34H3 Lecture Notes - Covalent Bond, Charged Particle, Homeostasis


Department
Biological Sciences
Course Code
BIOB34H3
Professor
--

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Lecture 1 1
Monday May 5, 2011
Ion
o Charged particle (extra or surplus of electrons)
Covalent bond
o Shared electrons
Physiology
o The study of how things work
o Things are very highly organized in mammalian physiology since we are complex
organisms
The ultimate activity of the nervous system is the behavioural response (i.e. putting on a
sweater when your cold)
Homeostasis
o Adaptive significance of functions so that things work normally
o Tries to keep internal environment stable
o Cells are exposed to different fluids which and change your physiology
Most cells contact cellular fluids
o Protective cells are on the outside
Control mechanisms try to get homeostasis re-established
o Failure to re-establish leads to illness and death
DNA methylation appears to be critical in determining if its working and can lead to cancerous
states
Tissues and organ systems all communicate with each other
Physiology is an integrative science
KNOW CONCTRATIONS OF IONS IN INTRACELULAR AND EXTRACELLULAR
Intracellular Concentration (mM)
Extracellular Concentration (mM)
Na+
5 15
150
K+
150
5
Cl-
9
125
Ca2+
0
2.4
P-
4
0.2
Cells are in dynamic equilibrium… inside are usually more negative (i.e. -70mM in neuron) than
outside
Cell membranes are selectively permeable ions move through channels in the membrane
o These channels are selective for specific ions
The electrical gradient is a charge difference between two points (electrochemical gradient)
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