BIOB51H3 Lecture Notes - Lecture 17: Aids, Multiple Drug Resistance, Reverse Transcriptase

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Aids: acquired immune deiciency syndrome, caused by hiv, can occur everywhere in your body. Treatments available to prevent onset of aids (posiive: many side-efects, not always efecive, require life-long medicaion. Aids accounts for 3. 1% of deaths worldwide > deaths from tb, respiratory cancers, or car accidents. Hiv does not atack any paricular group (gender, age) Unprotected sexual intercourse with an infected partner. Verical transmission (mother to child): utero; delivery; breast milk. Worldwide distribuion of hiv infecions various in areas: biology of hiv. Epitopes: viral proteins, displayed on surface of virion or infected cell (gp120, gp41) 1: when the host replicate it own dna, it will also replicate hiv dna. New virions: infect other cells in the same host, are passed to new hosts via body luids e. g. , oral, anal, or vaginal sex,intravenous drug use, childbirth, breast feeding. 1)selecion inside the body of each host (rapid replicaion favored: selecion across the populaion of hosts (maximum spread among hosts favored)

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