BIOB51H3 Lecture Notes - Lecture 10: Myoglobin, Zygosity, Nav1.7

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Lenski"s long-term evolution experiment: took a lot of single cell e. coli (with one genome) and put them in a nutrient-limited medium. In the experiment, 1 cell was placed into a low nutrient medium in order to reproduce. If relative fitness was equal to the ancestral line, it would equal 1. If the relative fitness was greater than the ancestral line, it would be greater than 1. If the relative fitness was less than the ancestral line, it would be less than 1. In this experiment, the fitness increases as time passed: however, there is variation among lines in relative fitness, the mutations that arise aren"t the same mutations for each line. Computer simulation: the alleles started from a very low frequency, the consistent selection leads to consistent directional change, the stronger the selection, the more rapid change occurs, significant changes in allele frequency can occur rapidly. It shows the human populations using data from 200 studies.

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