BIOC12H3 Lecture Notes - Lecture 2: Beta Sheet, Sodium Dodecyl Sulfate, Cytoplasm

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24 Oct 2014
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Crowded organelle, filled with proteins and a lot of water. Molecule can undergo collisions, different types of interactions: molecular crowding. Ampiphatic molecule: sodium dodecyl sulfate: hydrophillic and hydrophobic areas, detergent: traps dirt within hydrophobic area (tail), with a section of micelle that capture dirt and microorganisms, detergents by definition are antibacterial. Micelle (circle with outer hydrophilic inner hydrophobic) Bilayer vesicle ( double circle with one inner and outer layer of hydrophobic molecules with inner of circle being hollow) typical of way we form membranes. Formed by sharing of electrons (with exception of disulfide bonds) Weak interactions critical for structure/function of macromolecules. Proteins at various times in their life need to change their structure locally and too much energy to undergo small change in structure. All but hydrophobic interactions are electrostatic interactions. Can interact across largest distance than other noncovalent interactions. Strength of charge-charge interactions depends on the solvent.

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