BIOC14H3 Lecture Notes - Lecture 9: Gene Gun, Lentivirus, Nortriptyline

• School: UTSC
• Department: Biological Sciences
• Course: BIOC14H3
• Professor: Patrick Mc Gowan

Document Summary

Lecture 9 objectives: genetic influences on cognitive deficits, schizophrenia. Symptoms and prevalence: dopamine hypothesis, heritability, genetic components, autism. Symptoms, prevalence & heritability: genetic and environment components, mouse models of autism, mood disorders, prevalence, depression, monoamine hypothesis of depression, mouse models. Chapter 11: psychiatric disorders with a cognitive component. Lecture 9 objectives: anxiety, type of anxiety disorders, prevalence, diagnostic criteria. Ssri and anxiety: genetic influences, genetic counseling, tools and analysis, gene therapy. In vivo and ex vivo: techniques, examples, alzheimer"s disease, parkinson"s disease, eating behaviour. Chapter 14: genetic counseling, pharmacogenomics and gene therapy. Identifying genetic variants by risk allele frequency and strength of genetic effect (odds ratio) 4 very resistant to therapy, people on the street talking to someone thats not there. Symptoms may range from mild (sometimes hardly noticeable) to severe. Schizophrenia: generally similar prevalence country to country with ~0. 5-1% of the population, ~ 24 million people suffered from schizophrenia worldwide with about 280,000 in canada (2011 estimate)