BIOC33H3 Lecture Notes - Trachea, Cytosol, Aorta
Document Summary
Affected by sympathetic innervation, leading to enhanced levels of ca - lead to greater filament binding and sliding more contraction. Afterload a higher pressure - harder for ventricle to pump against this (blood pressure ) - if bp is high, the ventricle is pumping against: high bp leads to lower sv because pumping against higher pressure downstream. Amount of blood in ventricle at end of relaxation phase. 6 factors affecting: preload - pressure in vena system; if this pressure is higher, pushes more blood in atria and ventricle - get higher ventricular filling, venus pressure pushing blood into ventricles. = volume / pressure measure of how easily ventricle can stretch. High change in v for any change in p - have a compliant ventricle: stiffness. Small change in v for given change in p - heart will be stiff: diagram: Standard way in which seeing compliance curves.
