BGYB51H3 Lecture 10 Notes Oct 13
1
Page
86
Views
Department
Biological Sciences
Course Code
BIOC51H3
Professor
Maydianne Andrade
BGYB51H3 Lecture 10 Notes
-comparing mitochondrial DNA can be used to determine mutations/locus/generation
-mitochondrial DNA is more susceptible to errors and mutations than nuclear DNA
-mutation rates are variable because they depend on the accuracy of DNA polymerase
-DNA polymerase varies due to allelic variation and the fact that it is a synthesized protein
-mutation is a side effect of rapid cell division, which is a trade off of DNA replication
-high mutation rates are favoured in novel environments
-low mutation rates are favoured in similar and constant environments
-mutation strain is more successful in early infection due to novel environment
-when wild type strain adapts to novel environment, mutation advantage stops
-wild types eventually slow mutation to reach high level of fitness
-any factor that tries to reduce variation is a selective agent
-in most cases, strains of wild type and mutator bacteria will compete in a novel environment
for survival
-mutators are favoured in a new environment in competition with a wild type bacteria even
when initial inoculation gives a numerical advantage to wild types
-rapid DNA replication is beneficial to disease organisms
-gene duplication is one source for new genes during meiosis
- paralagous genes are duplicated genes may accumulate mutations that can acquire new
functional effects
-paralogous genes derive from a common ancestor
-orthologous genes are duplicated genes can result in the separation of lineages
-uµ]}v}v[µ]Pv](]vZvP]n allele frequencies
-synapomorphies are homologous traits that define a particular lineage
-neutral mutations result in divergence of lineages and can be analyzed by a molecular clock
www.notesolution.com
Loved by over 2.2 million students
Over 90% improved by at least one letter grade.
OneClass has been such a huge help in my studies at UofT especially since I am a transfer student. OneClass is the study buddy I never had before and definitely gives me the extra push to get from a B to an A!
Leah — University of Toronto
Balancing social life With academics can be difficult, that is why I'm so glad that OneClass is out there where I can find the top notes for all of my classes. Now I can be the all-star student I want to be.
Saarim — University of Michigan
As a college student living on a college budget, I love how easy it is to earn gift cards just by submitting my notes.
Jenna — University of Wisconsin
OneClass has allowed me to catch up with my most difficult course! #lifesaver
Anne — University of California
Description
Related notes for BIOC51H3
