BIOC33H3 Lecture Notes - Thoracic Vertebrae, Thoracic Cavity, Carbonic Anhydrase

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1 Mar 2014
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Adrenergic regulation: catecholamine action, in humans, catecholamines circulating are good regulatory systems for heart and blood pressure, decrease in blood pressure is sensed by baror in carotid arteries and aortic arch, catecholamine regulation . Adrenergic regulation of bp (tpr: when looking at catecholamine hormones, when nad and ad are released, can act on 2 major pop"n of r: alpha and beta. Alpha 1,2 beta 1,2: activate second messenger systems - when ad or nad work on alpha-r it leads to vasoconstriction and when working on beta-r - vasodilation. Nad from sympathetic nerves (neural: when nad is released as a nt from sympathetic nerves outcome = vasoconstriction. This is because alpha adrenoceptors are located mostly on smooth muscle being innervated by sympathetic nerves. Nad finds itself interacting more with alpha r. Alpha-r on blood vessels tend to be found around sympathetic nerve terminal endings: promote vasoconstriction when stimulated.

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