BIOD27H3 Lecture : BGYB30H3 Lecture 23 Notes Reproduction and Development 3-Nov 26
11 Aug 2010
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BGYB30H3 Lecture 23 Notes
-spermatogoniµuW primary spermatocyte W secondary spermatocyte W spermatids
-it takes 64 days for spermatogonia to mature
-spermatogonia undergo mitosis in the basal lamina and meiosis in the lumen of the
seminiferous tubules
-blood-testes barrier are tight junctions that break and reform while spermatocytes migrate
-spermatids
x lose cytoplasm and develop flagellated tail
x chromatin of nucleus condenses into a dense structure
x acrosome develops and contains enzymes that breakdown oocyte wall for fertilization
- during ejaculation, sperm released from the seminiferous tubules moves through the vas
deferens to the urethra
Sertoli cells
x provide nourishment
x secrete inhibin, activin, enzymes, growth factors and androgen-binding protein (ABP)
x ABP binds to testosterone to make it less lipophillic and keep it in the lumen
Leydig cells
x Found in the interstitial fluid between the seminiferous tubule
x secretes testosterone that can be converted to estradiol
-LH is regulated by GnRH hormone while FSH is regulated by activin, inhibin, and GnRH
-FSH activates receptors in Sertoli cells to release ABP and enzymes to control spermatogenesis
-ABP binds to testosterone in the lumen to initiate maturation of sperm
-LH stimulate Leydig cells to release testosterone that stimulates Sertoli cells
-spermatocytes only respond to testosterone if its bound to ABP
-external female genitalia of the female is called the vulva
-labium major is equivalent to scrotum in males while labium minora is equivalent to the
shaft of the penis
-uterus is the site where fertilized egg is implanted during pregnancy
-the three layers of the uterine wall are
x connective tissue: thin layer
x myometrium: thick middle layer
x endometrium: varies in thickness depending on the stage in the menstrual cycle
-fimbrae are held to the ovary by connective tissue to connect the ovary to the Fallopian tube
-cilia in the Fallopian tubes move the oocyte to the uterus
-outer cortex of ovary contains ovarian follicles while the central medulla contain nerves and
blood vessels
-ovary produces gametes and hormones
-primary oocyte is encased in follicles that are covered by granulose cells and thecal cells
-ovulation occurs when egg is released from the follicle
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Document Summary
Spermatogonik9 primary spermatocyte 9 secondary spermatocyte 9 spermatids. It takes 64 days for spermatogonia to mature. Spermatogonia undergo mitosis in the basal lamina and meiosis in the lumen of the seminiferous tubules. Blood-testes barrier are tight junctions that break and reform while spermatocytes migrate. N chromatin of nucleus condenses into a dense structure. N acrosome develops and contains enzymes that breakdown oocyte wall for fertilization. During ejaculation, sperm released from the seminiferous tubules moves through the vas deferens to the urethra. N secrete inhibin, activin, enzymes, growth factors and androgen-binding protein (abp) N abp binds to testosterone to make it less lipophillic and keep it in the lumen. N found in the interstitial fluid between the seminiferous tubule. N secretes testosterone that can be converted to estradiol. Lh is regulated by gnrh hormone while fsh is regulated by activin, inhibin, and gnrh. Fsh activates receptors in sertoli cells to release abp and enzymes to control spermatogenesis.
