BIOD27H3 Lecture 6: Lecture 6
27 Apr 2011
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W physiological role of neurotransmitters and receptor subtypes www. notesolution. com. Neurotransmitters: can be classified based by chemical composition: amines, amino acids, acetylcholine. __na synthesized________________: neurotransmitter __into synaptic cleft__taken back up by _active transport___, excess neurotransmitter is ___broken down (catabolism)__by enzyme in the. Figure 8. 22: acetylcholine (ach) is made from choline and acetyl coa in mitochondria. In the synaptic cleft ach is rapidly broken down by the enzyme acetylcholinesterase into choline and acetate: choline is transported back into the axon terminal and is used to make more ach www. notesolution. com. Taken up into presynaptic terminal by transporter (active reuptake) recycled into sv or broken down. Taken up into presynaptic terminal by transporter (active reuptake) and broken down or repackaged into synaptic vesicles www. notesolution. com. W there is a finite number of receptors. W at low concentrations, there is a linear relationship between nt concentration and amount of neurotransmitter bound to the receptor.
