Class Notes (810,487)
Canada (494,138)
BIOA01H3 (687)


3 Pages
Unlock Document

University of Toronto Scarborough
Biological Sciences
Mark Fitzpatrick

DNA replication - Conservative – parental helix remains intact and a second all new copy is made - Semi Conservative – two strands of the parental helix separates and each functions as a template for synthesis of a new complementary strand - Dispersive – mixture of old and new synthesized parts - DNA replicates Semi conservatively - In prokaryotes since they have circular DNA there is only one origin of replication - In eukaryotes they have linear DNA which allows there to be many origins of replication - There are 5 steps to replicate DNA 1. Helicase (an enzyme) unwinds the helix 2. Single stranded binding proteins (S.S.B.P.) help keep DNA open and unwound 3. The leading strand is synthesized continuously; made 5’ è 3’ but is read as 3’ è 5’ by DNA Pol. III 4. The lagging strand is synthesized in fragments called Okazaki fragments which are made in a process similar to 2 steps forward, 1 step back. RNA primes made by RNA primase flag the DNA Pol. III 5. The DNA Pol I replaces the RNA primers with DNA 6. DNA ligase joins Okazaki fragments 7. Gyrase relases tension generated by the uncoi
More Less

Related notes for BIOA01H3

Log In


Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.