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Lecture 6

Lecture 6 Study Guide

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Biological Sciences
Mark Fitzpatrick

Chapter 6: Enzymes 6.3 What are Enzymes? N The reactions that occur in cells are slow and need catalysts J substances that speed up a reaction without being permanently altered by that reaction N Enzymes J specialized group of proteins that catalyze reactions N Generally, reactions proceed only after the reactants receive enough energy to surpass the activation energy requirement N Enzymes are very specific (substrate-specific) and this specificity is determined by the 3D shape of the enzyme N Reactants are called substrates J they bind to the active site of the enzyme N The binding of a substrate to the active site produces an enzyme-substrate complex held together by one or more means N The enzyme lowers the activation energy required, offering the reactant an easier path to take N @Z]Lo]o]]K}ZL[ ZL2Z]L }ZZ}LZZZoo sped up N No difference in free energy between catalyzed and uncatalyzed reactions 6.4 How do Enzymes work? N Enzymes orient substrates o Bringing together atoms that will bond and bond only in that orientation o Example: acetyl CoA and oxaloacetate to form citrate N Enzymes can st
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