BIOA01H3 Lecture Notes - Lecture 26: Chromatin, Nucleosome, Metaphase

• School: UTSC
• Department: Biological Sciences
• Course: BIOA01H3
• Professor: Monica Sauer

Document Summary

Single origin, the replication fork move to the opposite side until they meet. Slide 3: prokaryotes cells undergo a binary fission. Start at the singe origin: all the protein are gather in the middle of the cell, the two replication forks goes around the entire circle. F plasmids allow the bacteria to have sex. Protein associated with dna are two types: histones and non-histones. Histones: small-positively charged (basic) proteins complexes with dna: positive charge amino acid, attaches to dna because negative charge of dna backbone, compacts dna in nuclei and regulates dna activity. Metaphase chromosome: during mitosis or meiosis, chromatin fibers fold and pack into thick, rod like chromosome. Take the dna wraps it around the core of histones molecules: wrap around twice, this forms a nucleosome, four histones in a core, 10 nm in size. Take the bead necklace wrap it around and forms a solenoid.