BIOB11H3 Lecture Notes - Tyrosine, Glycogen, The Sequence

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17 Jan 2013
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Bio b11 lec 23 c15 signal transduction iii. Don"t memorize these, just be aware of em. Fig 15-26: ca2+ floods cytoplasm of cardian muscle cell. Yellow thing = membrane bound pumps, use atp. A depolarization in membrane voltage causes the opening of voltage- gated calcium channels in the plasma membrane, allowing entry of a small amount of ca2+ into the cytosol (step1). The calcium ions bind to ryanodine receptors in the ser membrane (step 2), leading to release of stored ca2+ in the cytosol (step3), which triggers the cell"s contraction. The ca2+ ions are then removed from the cytosol by the action of ca2+ pumps located in the membrane of the ser (step4) and a na+/ca2+ secondary transport system in the plasms membrane (step 5), which leads to relaxation. This cycle is repeated after each heart beat. You have an egg and a sperm, the sperm fertilizes the egg, result is a diploid single cell organism, rapid series of divisions.

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