BIOB11H3 Lecture Notes - Lecture 4: Ribonucleoside, Archaea, Bond Energy
15 Mar 2013
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Document Summary
The enzymes responsible for transcription in both prokaryotic and eukaryotic cells are called. Enzymes are able to incorporate nucleotides, one at a time, into a strand of rna whose sequence is complementary to one of the dna strands, which serves as the template. The steps in the synthesis of rna include: first, the association of the polymerase with the dna template (interaction between two different macromolecules = proteins + nucleic acids) Cellular rna needs the help of additional proteins called transcription factors which help recognize the promoters: rna polymerase moves along the template dna strand toward its 5" end. As the polymerase progresses, the dna is temporarily unwound, and the polymerase assembles a complementary strand of rna that grows from its 5" terminus in a 3" direction. This condition is met during transcription with the aid of a second reaction.
