BIOB11H3 Lecture Notes - Lecture 11: Zinc Finger Transcription Factor, Leucine Zipper, Dna-Binding Domain

79 views22 pages
18 Mar 2013
School
Course
Professor

Document Summary

Lecture 11 -gene regulation ii: transcription factors and microarray. Vocabulary: transcription factor types/dna binding and activation domains/hetero vs. homodimer/ combinatorial control/microarray technology. Today will talk about transcription factors and something used in genomics called microarray technology. Microarray technology is a high input genomics technique that can be used to examine the expression of every gene in an organism at the same time. So if an organism has 25,000 genes, using microarray technology you can find out what"s happening with each of those at once. Transcription factors are proteins they are trans acting factors that diffused through the nucleoplasm or in bacteria through the cytoplasm of the cell and they have at least two functional domains. The first has to do with their role in transcription and one of their domains is referred to as the dna- binding domain. This is a sequence specific interaction of this particular protein with a specific dna sequence.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents