BIOB11H3 Lecture : Genome Evolution
Document Summary
Transposition-movement of dna segments from one place on a chromosome to an entirely different site. Transposon- dna segments capable of moving from one place in the genome to another. Retrotransposon- transposable elements that require reverse transcriptase for their movements within the genome. Reverse transcriptase- an rna dependent dna polymerase, an enzyme that uses rna as a guide to synthesize a complementary dna strand. Genetic maps- assignment of genetic markers to relative positions on a chromosome based on crossover frequency. Polymorphism- sites on the genome that vary amongst individuals. Rflp- a base change that result in the abolition or cretion of a recognition sequence for a restriction enzyme. Snp (single nucleotide polymorphisms)- sites in the genome where alternate bases are found with high frequency in the population. Most common genetic variability in humans occur at snps. Snps thought to have arisen from a mutation that happened once in during the course of human evolution o.
