BIOB12H3 Lecture Notes - Lecture 5: Collagen, Hsp70, Chloroplast
18 May 2012
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Intermediary metabolism (degradation and synthesis of small molecules) Not an organelle (cytosol-mitochondria-rough er- smooth er, nucleus peroxixomes, lysosomes, endosomes) *organelle: a subcellular compartment or large macromolecular complex, often membrane-enclosed, that has a distinct structure, composition, and function. *endosome: endocytosis, absorbs other molecules by engulfing them. *rough er is the most abundant membrane in eucaryotic cells. +topologically equal spaces are in pink in the diagram. *3 mechanisms of moving from one organelles to another: gate transport. Move b/w cytosol and nucleus through nucleus pore complexes (a selective gate) in nuclear envelope: transmembrane transport. Transmembrane protein translocatiors directly transport specific proteins across a memebrame from cytosol into a space that is topologically distinct. Ex) protein from cytosol into the er lumen or mitochondria: vesicular transport. A spherical transport vesicles ferry proteins from one compartment to another. They discharge by fusing with the membrane of . Ex) transfer of soluble protein from er to golgi apparatus.
