BIOB32H3 Lecture Notes - Central Canal, Endosteum, Long Bone

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The skeletal system includes: bones of the skeleton, cartilages, ligaments and other connective tissues that stabilize and connect. Functions of the skeletal system: support, storage of minerals and lipids, blood cell production, protection, leverage. Bone shapes: long, flat, short, irregular, sesamoid, sutural. Bone structure = two types of bone: compact bone (dense, spongy bone (cancellous) A typical long bone includes: diaphysis, epiphyses, metaphysis, articular cartilage, marrow cavity, filled with red or yellow marrow. Osseous tissue: supporting tissue with a solid matrix, crystals of hydroxyapatite, minerals deposited in lamellae, covered by periosteum. Cells in bone: osteocytes = mature bone cells, in lacunae, connected by canaliculi, osteoblasts synthesize new matrix, osteogenesis, osteoclasts dissolve bone matrix, osteolysis, osteoprogenitor cells differentiate into osteoblasts. Compact bone and spongy bone: basic unit of compact bone is an osteon, osteocytes arranged around a central canal, perforating canals extend between adjacent osteons, spongy bone contains trabeculae.

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