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Lecture 10

BIOB32H3 Lecture 10: Lecture 10

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Biological Sciences
Kenneth Welch

BIOB32- Lecture 10 - The neurons or the axon of the neuron determines how fast the signal is propagated- depends on how well the sodium channel is imported into the axon, - The potassium that is coming out is the offsetting of depolarization - If you have a bigger tube, it will easily permit the flow of charge along the inside of the axon - The axons of the squid can be about 1 mm wide and this is long enough to stick something into the axon, we don’t need some fancy equipment and microscope for that - This is not the case of all animals because not all of the have the space - We have insulating cells that hope to prevent the nuclear charge across the membrane , in peripheral nervous system the Schwann cell does the same thing - Myelin cells reduces the, we are increasing the resistance to flow through. we are also reducing membrane capacitors  tendency of them to line up along the membrane inside and outside - The inside is relative negative compared to the outside - The distance along the electrical organisation increases Saltatory conduction - The action potential wave is not a continuous wave that continues along - Instead there is the jumping of action potential from one side to the other - The greater potential is great enough to allow depolarization to that threshold value to the next node of ranvier – action potential initiates there and so on and so forth (excitable) cell-to- cell communication - This involves the understanding of synaptic function - With relatively small amount of them we can begin to develop relatively relative amount of the circuit, circuits that can turn other circuits on or off Electrical synapse - The simplest form of synapses - We have the membrane of two different cells that are very very closely aligned with each other and they are connected with the gap junction - 1 connexion molecules open 6 connectin molecules - When they are open they can allow relatively small molecules to pass in and out - This is the fastest type of synapse because we do not have an additional step - We would see a high intensity of gap junction , this can connect other neurons as well - We want all the muscles
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