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BIOB34H3 (271)
Lecture 1

BIOB34H3 Lecture 1: 23

14 Pages
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Department
Biological Sciences
Course Code
BIOB34H3
Professor
Blake Richards

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Description
12202015 OneNote Online Muscles Friday, December 18, 2015 1:05 AM Myosinmolecular motor, captures and converts chemical energy of ATP into the mechanical energy of movement interacts with actin Contractile proteinsmyosin and actin Muscles can be smooth (unstriated) or striated Striations are caused by sarcomeres Skeletal muscleattached to bones Cardiac musclemake up heart Smooth muscleorgans Bundles of muscle fiberscells make up skeletal muscle Tendonsattach muscle to bone transmitting force generated by the muscle fibers to the skeleton Single muscle fibers can be as long as 0.3 m (1 ft) Single fibers are 10 to 100 micrometers (m) in diameter in some species it can reach several hundred micrometers in diameter Skeletal muscle is multinucleated Myoblastsfusion of individual uninucleate cells Sarcolemmacell membrane surrounding muscle fiber Myofibrilshas regularly repeating, transverse bands A bandsdarker portions of myofibrils I bandslighter portions of myofibrils Z lines H zoneonly thick filaments appear M linein the middle of H zone Sarcomerespace between z lines One myofibril = longitudinal series of repeating sarcomeres Two types of myofilaments: Thick filamentcomposed of myosin, with actin make up A band of each sarcomere Thin filamentcomposed of actin, make up I band of each sarcomere, anchored to Z line https:adminmailutorontomy.sharepoint.compersonalhema_potluri_mail_utoronto_ca_layouts15WopiFrame.aspx?guestaccesstoken=0NXnTejTLtMMJI 114
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