BIOB34H3 Lecture Notes - Subthalamic Nucleus, Hemiballismus, Dysautonomia

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22 Apr 2013
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Parkinson"s disease (also known as parkinson"s, parkinson disease, or pd) is a degenerative disorder of the central nervous system that impairs motor skills, cognitive processes, and other functions. Pd is the most common cause of chronic progressive syndrome characterized by tremor, rigidity, bradykinesia and postural instability. Among non motor symptoms are autonomic dysfunction and sensory and sleep difficulties. Cognitive and neurobehavioral problems, including dementia, are common in the advanced stages of the disease. Pd usually appears around the age of 60, although there are young-onset cases. Pd = condition that slowly freezes the body. Prescribed drugs to unlock the limbs side effects = twitching movements for which there is little treatment = no cure for pd yet. Pd = missing dopamine cells which make this are dying = this is what leads to paralysis. 1960"s = found a way to replace dopamine = l dopa mobility returned in pd patients!

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