BIOC15 Lecture 1 Wednesday
September 4, 2013
Russell et al. 2010
□ Many of the discoveries in genetics are found using other
□ Agriculture and horticultural genetics are things that may be
important with metabolic diseases (yeast); agriculture and
□ Mice are used frequently because it is a mammal – closest
approximation to human genes
□ Peas – Gregor Mendel, beginning of genetics using pea plants
□ Zebra fish – developmental genetics
□ Variety of different spheres used in genetics
General Course Information
□ Genetics is like learning a language
- Do not simply memorize – no idea how to use the term
□ Don’t memorize solutions to the problem
- Cases differ
- Look at patterns for solving problems
□ Genetics: Transmission of traits from one generation to the
□ Central Dogma of biology: DNA to RNA to proteins
□ Gene regulation – what stops transcription?
□ What is a gene? – possible test or exam question
- Carries information of a genotype and phenotype
- Used for protein synthesis
- Part of DNA
- Definition is deep and complicated; a concept to be
- What happens when we change a gene?
- Who is Mendel?
- Gene location on chromosomes (within or not within a
- What happens when genes get altered and changed?
How genes control uncontrolled growth such as cancer?
- Genes in different populations
- Genes as little defined units but think of the contribution
of many genes that build a trait such as height or
behaviour ability to read primary literature of genetics - DNA phenotypes and populations
Genetics: GK genos birth, n (1905)
□ Genetics com