BGYB30H3 Lecture 12 Notes Sensory 3-Oct 20

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University of Toronto Scarborough
Biological Sciences
Ingrid L.Stefanovic

BGYB30H3 Lecture 12 Notes -olfaction is the system underlying how we sense and perceive odor -the olfactory epithelium contains olfactory receptorsprimary olfactory neurons -primary olfactory neurons have free nerve endings and are found in the mucus membrane of the nose -primary olfactory neurons move through the olfactory tract to the olfactory bulb where they synapse unto secondary olfactory neurons -all sensory systems have support cells -stem cells (basal cells) are located in the olfactory epithelium and replace dead olfactory neurons -olfactory bulb processes and integrates info from the primary olfactory neurons in the nose -secondary olfactory neurons terminate in the olfactory cortex, which sends info to the amygdala and the hippocampus (triggers emotional response and memory of the odor) -odorant molecules dissolve and penetrate the mucus to bind to certain odorant receptors that are sensitive to these molecules -odorant receptors are GPC receptors that are linked to G-olfaction protein (increases cAMP) -each olfactory cell contains different odorant receptors -olfactory bulb integrates and decodes info about dominant smells from the primary olfactory neurons -the five main taste receptors of the gustatory (taste) system are salty (activated by the presence of sodium ions), sour (activated by presence of hydrogen ions), bitter (seen as potentially toxic), sweet (seen as nutritious),
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