BIOD33H3 Lecture Notes - Lecture 8: Blood Plasma, Cortisol, Hepatocyte
Document Summary
Cortisol binding to the glucocorticol receptor is playing an important role in allowing fish to accommodate to sea water. Cortisol may also bind to other receptors. In fish, prolactin promotes fresh water acclimation in euryhaline fish: prolactin levels are highest from fish that go from saltwater to freshwater, fish kept in freshwater are also high. The hormone itself changes in level: cortisol levels did not increase (cortisol is a stress hormone) Second prolactin receptor has one huge initial change in fish moving from fresh water into sea water: the mozambique tilapia does move very well from fresh water into seawater. May have something to do with the changes in the prolactin receptor expressions. Cortisol for sea water, prolactin for fresh water. Apoptotic ratio in epithelium and connective tissue: apoptotic cells (tunel) allows to visualize dead cells, when injecting cells with cortisol, there is a significant amount of cell death.
