BIOD33H3 Lecture Notes - Lecture 2: Brown Adipose Tissue, Ventricular Hypertrophy, Partial Pressure

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17 Oct 2016
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Metabolism of deer mice is higher at higher altitudes (thermoregulation) At high altitude, see greater quantities of brown fat. Highlander mice had higher maximal metabolism under hypoxic conditions, as well as normoxic conditions. May be an aerobic scope trade-off: field metabolic rate (fmr) for highlander mice is running at close to max, lowlander mice can vastly increase from fmr to max, luxury metabolism. In mammals, muscles are made of mixed types of fibres: slow oxidative fibres. Slow contraction fibres, slow myosin atpase activity. Endurance-type activities (e. g. running a marathon; maintaining posture: fast glycolytic fibres. Short-term intense or powerful movements (e. g. , hitting a baseball) Stain muscles for particular biochemical feature, characteristic of each muscle type: sdh (enzymes of oxidative metabolism; linked with oxidative metabolism) Purple in figure is of muscle with sdh. See more sdh positive fibres in highlander mice. Highlander mice have muscles with more oxidative fibres: slow myosin atpase. Dark orange is an oxidative type of muscles.

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