BIOD35H3 Lecture Notes - Lecture 3: Mean Arterial Pressure, Vo2 Max, Hemorheology

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Re-distribution of blood flow: increases in skeletal muscle, heart, brain, and skin, decreases in kidneys, gi tract, and others. Ateriovenous oxygen difference (a-vo2) is the difference in the oxygen content of the blood between the arterial blood and the venous blood. Good way to see how much o2 is delivered and used by muscle. Major limitation to an individuals ability to conduct high intensity exercise. Mean arterial pressure (map: represents the force driving blood through the system, average pressure of the arteries (not venules or veins, map = q x total peripheral resistance (tpr) Dependent on vasoconstriction/vasodilation of the artery: map = (sabp + 2dabp) / 3 (units are in millimetres of hg) Systolic blood pressure + 2 diastole blood pressure. Diastolic - rested (filling with blood: feed-forward regulation - anticipation initiates change. Q and arterioles: local chemical factors can trigger vasodilation of arterioles.

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