BIOD35H3 Lecture Notes - Lecture 2: Breathing, Peripheral Chemoreceptors, Nasal Cavity

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Exercise imposes a massive stress to the body. Selyes" model of explain the short term effects of exposure to stressors: also accounts for the long term implication of prolonged exposure to a stress. Seyles" model of adaptation shows how the body responds to and overcomes stress: the sweet spot for muscle-growth and strength gains hovers between alarm reaction and resistance, without diverse training, you can wander into exhaustion. With every stress, the body needs time to adapt. Gas exchange: pressure difference between inspired air and our alveoli. Neural factors for ventilation control at rest: medulla - respiratory centre, receives afferent feedback from chemoreceptors and baroreceptors, send the appropriate efferent response to the ventilation muscles. Humoral controls of ventilation: plasma po2 and peripheral chemoreceptors. Peripheral chemoreceptors provide the site for detecting arterial hypoxia and initiating a ventilator response. Pao2 drops below 60 mmhg (partial pressure of alveolar oxygen)

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