CHMB16H3 Lecture Notes - Lecture 8: Conjugate Acid, Acid Dissociation Constant, Sodium Carbonate

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10 Sep 2013
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1: dr. keerman uses 100mm nacl to balance the ionic strength of a buffer solution i. e. to bring the ionic strength closer to physiological serum ionic strength. Dissociation of water (ion-product constant: water undergoes autoprotolysis so at 25 degrees c, the ph of water is 7 (neutral) but. 2 so the ph is 6. 98 instead of 7 because activity numbers can change depending on the temperature of solutions the value of kw depends on the solution"s temperature: dissociation increases with increasing temperature ** Solutions of h2a treat h2a as a monoprotic acid with ka=k1 solve eq as weak acid: use k2 eq to solve for [a2-] Isoelectric and isoionic ph isoionic ph = ph obtained when a pure, neutral, polyprotic acid (ha) is dissolved in water: example: alanine dissolved in water. 9 the isoelectric ph = ph obtained when the average charge of the polyprotic acid is 0.

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