CHMC47H3 Lecture Notes - Acetic Acid, Thiamine, Ammonium Nitrate
Document Summary
The three-step synthesis of the antiepilepsy drug dilantin. Dilantin was synthesized in a three-step process involving benzoin synthesis, oxidation of benzoin to. The melting point range of dilantin was 290-293 c and actual yield of 12. 5 %. The slightly depressed melting point range indicated some impurities were present. The structures of benzoin, benzil and dilantin were characterized by melting point, mass spectrum, ir and 1h-nmr spectroscopy to determine the efficiency of the synthetic procedure. Epilepsy is the most prevalent neurological disorder, affecting approximately 50 million people worldwide. 1 it results from a temporary electrical disturbance of the brain. 1 epilepsy is a disorder of the central nervous system characterized by excessive electrical discharge. 2 a typical seizure may include brief and periodic episodes of change in the normal state of consciousness, loss of muscle tone, and sensory and behavioral alterations. 2 dilantin is an anticonvulsant which plays an important role in treating patients with epilepsy.
