EESA10H3 Lecture Notes - Lecture 4: Miscarriage, Endocrine System, Sex Organ
15 Mar 2018
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Eesa10 - lecture 4 - chemical hazards and human health. Endorcrine system - produce hormones (regulation of functions) It is hard for the endocrine system to differentiate the internal hormones to the external hormones. Toxicology data mostly from animal studies, not much from human exposure: direct effects: Changes in the level of produced proteins: indirect effects: Synthetic estrogen used by physicians to prevent spontaneous abortion (1948-1971) Administered for early pregnancy until 35 weeks. > 1million women took it between 1960-1970. Daughters whose mothers took des have increased incidents of : Research support the hypothesis that exposure to pesticides may affect the development of intelligence and motor skills of young children. This study compared two groups of rural yaqui indian preschoolers in mexico, one frequently exposed to pesticides, the other rarely exposed to pesticide. Quantity of chemicals accumulated in the body. Not possible to detect if present in very low concentrations. Dioxins have no commercial usefulness by themselves.
