EESA10H3 Lecture Notes - Lecture 4: Endocrine Disruptor, Thyroid, Pituitary Gland

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B/c they just look like hormones as a result of disruption; numerous health probs thus call these endocrine disruptors; disrupt normal hormone func very little is known about these chem from human research. Endocrine disrup every hormone recep binds to protein; proteins are recep and carry hormones to place where they will work since recep recog hormones; they also recog chem which mimics. Thus there are probs in genes, proteins, dna. If there is prob w/ genes, there is prob w/ protein synth. So about 20-30 yrs after adults are less sensitive to hormonal dysfunc but mother and fetus hormones are important for develop. Health impacts when using ddt for 1st time: domestic roosters start changing and getting femme characs over time now, many other animals such as frogs, crocs, fish change from m to f. Thyroid dysfunction: 2nd ex on how adults are less sensitive than fetus. Thyroid gland produces hormones: t1 and t2 hormone.

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