EESA10H3 Lecture : Week 10 Lecture

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The science which studies toxic substances or poisons, that are substances which cause alteration or perturbation in the function of an organisms leading to harmful effects (truhaut, 1974) Poisons are compounds and cause negative impacts on human health. Toxicology: assessing chemical hazards (1: how harmful a substance is depends on: Chemical properties of the substance: electronegativity, polarity water is polar (has negative and positive side), all chemicals that are polar dissolve well in water, while non-chemicals are not dissolvable in water, relates polarity to solubility. Antagonistic = when one chemical reduces the toxicity of another one. Some vitamins (a and e) may reduce human reaction to some carcinogens. Synergistic = when two chemicals are together, one of them become more toxic: e. g. smoking in the presence of asbestos, multiple chemicals food additives, pesticides, air pollution, receptor, dose www. notesolution. com, response. Acute dose refers to single dose, usually high. Chronic dose repeated or continuous low dose over time.

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