EESA10H3 Lecture Notes - Lead, Covalent Bond, Insomnia
Document Summary
Naturally occuring extracted from the earth in ore. Accumlate in selectt tissues: nails, hair toxin in low conc. Classification of metals (toxicity: class b > borderline > class a) Class a: k, na, ca, mg, macronurtient (essental for life, low toxicity, form ionic bonds (+2 and +1) Hg, ti, pb, ag, au: nonessential, covalent bonds, very toxic form organometallics. Borderline: cr, cu, as, co ni, zn, mn ,fe, micronutrients. Blocking essential functional groups: protiens or enzymes. Resistance- species develop mechanism to no uptake metal. Tolerance- the capacity of species to withstand level of metals. Mechanisms: binding to nonsensitive compound, transformation to less toxic form, tolerance. Routes of exposure inhalation injestion through the skin. June 10, 2013 causes damges to the brain kidney some carcinogens. Very toxic filling (dentist: no impact tuna fish, effects central nervous system, tremor of the hands, memory loss, insomnia wood preservatives.
