GGRB28H3 Lecture : lecture 4

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2 Nov 2010
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1 million malaria related deaths (>90% in africa) most malaria forms do not lead to death disability from severe forms of the disease (to the brain, coma) 1/5 of the world population is at risk of malaria (over 100 endemic countries) 300-500 million cases of malaria per year parasite: plasmodium falciparum/vivax/ovale/malariae vector: female anopheles mosquito. Develops within mosquitoes bites passes parasite. Sporozoites into liver, multiplies, moves into blood, attacks red blood cells. * acute disease non-severe acute febrile disease cerebral malaria death. Ddt, temperature declines, filling marshes endemicity: intensity of malaria transmission in a location. ~1/50 results in the severe form of disease. ~1/5 of severe malaria leads to death (1 - 2 million a year) 20% of all childhood deaths (under 5) 975 000 children (< 5), 100 000 women estimated to die each year. 20. 3% - leading death of all children in the african region.

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