Lecture 3 Notes
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HLTA031H3 : Plagues and People
Tuesday, May 24 2011
*all video segments are testable material.
Leprosy is also know as hansens disease
Recorded throughout history , very old , documented in
several for different civilizations
Egpytian Papyrus (1550) BC
Indian Writings (600) BC
Alexander the Great returned from India
NO REAL ORIGIN : come plausibly from the far East.
Mentioned in Christian bible.
Disease of soul, and misinterpreted by people; lepers were
shunned by society. Situations: special clothing
(EUROPE) , had to have a bell (notify of arrival) , had to
live in colonies. Straught to post and burned alive, some
people were burnt alive. SPECIAL HOUSES “
leprosariums , lazaretto , leper colony , lazar house “
First leper house : 936 AD , 19000 peak of epidemic (13th
century ) lost civic status ,and removed from public
service ; special masses .
Some people were considered DEAD. “inhertience was
separated” spouse was not able to remarry .
Peoples face changed , that’s how they knew they were
leperors. Eventually decline : 1350 (16th century)
Take your time and read “MASS OF SEPERATION” an
actually ceremony ;
Page 309 ; Dr. Amauer Hansen of Norway in 1873.
Under a Germ Under A Microscope : Mycobaterium
leprae ; is now called hansen’s disease.
It cannot be grown in tissue , it only grows in mice and
armadilios because of low body temperature.
ROD SHAPED SPOR ; slow multiplying bacillus 12-14
days (Average doubling time )
Leprasay has an incubation period from 3-5 years
Transmitted via droplets from nose during frequent
contact ; it is not highly infectious ; low pathengencity.
Mainly affects the skin , nerves , and mucuous membranes ;
deformation of nose .
Peaked around 2001 , and it’s on the decline for the past
two years. Were stable and we know how to treat it well .
Numbers are very close 22-27 per 100,000 cases in brazil,
areas in south east asia , and some areas in Africa.
AFRICA : CONGO TANZANIA ANGOLA : area for
concern by WHO.
Anybody is at leprosy ; all races all around the world. Most
common in warm, wet areas , 10-14 , and 35-44 (more
susceptible) rare in infants.
CLINICAL MANIFESTATIONS : 836-837
Shows up in different forms , or it gets worse , or better :
range of factors. Depends on Immune System ; males are
INDETERMINATE (IL) : earliest and mildest , usually few
lesions ; on back . loss of sensation is rare.
TUBERCULOID (TT) : larger lesions on skin , loss of
sensation (not able to feel) , nerves are effected , nerves
become thicker , nerve damadge , progression can occur
resulting in borderline-type leprosy ; RARE to revert back
Less maliglinat type
BORDERLINE TUBERCULOID (BT)
Similar to tuberculoid , has smaller numerous lesions ,
more red , a lot more nerve damadge , smaller and closer
Lesions are really numerous in numbers , skin is clearly
disturbed , papules, plaques , and nodules ; any shape and
form , inverted saucers are common ; may remain in this
stage it may progress.
Never reverts back to less severe from ; they will never get
better on their own ; numerous lesions , nasl stuffiness ,
discharge and bleeding , swelling of legs and ankles , ; skin
thickens , eyebrows and eyelashes are lost , nose
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