HLTB21H3 Lecture 7: Lecture 7 In-class Notes [Measles]

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31 Oct 2010
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Earliest description is attributed to rhazes (900ad) - separated smallpox and measles clinically but thought they proceeded from the same cause. Prevailing theory was that the red rash represented the mother"s menstrual blood that accumulates during the child"s stay in the womb. Disease was welcomed - a way for the child to rid himself of the so called poision". Began in 1670, with thomas sydenham"s (also known as father of clinical ovservation") description of his son"s attack. He was the rst to clearly separate measles from smallpox, and he recognized complications such as cancrum oris (noma disease that leads to the destruction of tissue around the mouth) and encephalitis (in ammation of the brain) At the same time, scientists rejected the mother"s blood theory. Francis home (1757) demonstrated the infective nature of measles - succeeded in transmitting measles using blood from an infected child (8/10)

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