HLTB21H3 Lecture Notes - Lecture 4: Otto Von Bismarck, Miliary Tuberculosis, Mortality Rate
Document Summary
Description (8000 4000bc) tb limited to animals prehistorically (2400 bc) evidence of tb found in mummies: pott"s disease (tb of spine. & bone) (800bc) homer - phthisis" or consumption" (460 bc) hippocrates - disease due to evil air but not contagious (384 322bc) aristotle due to bad and heavy breath" (ad 500 1500) claims of royal supernatural powers. Disease (mid-19th century) tb was romanticized: operas: la traviata (1853), la. Boheme (1895). (1854) - jean-antoine villemin -specific microorganism as cause (1882) dr. robert koch mycobacterium tuberculosis, developed. Agent: mycobacterium tuberculosis (acid-fast bacillus), difficult to see because of waxy cell wall. Type 1 found in india; least virulent. Type a africa, china, japan, europe, north america. Type b exclusively in europe and north america. 1/3 of the world"s population is infected with the tb bacillus. 30 m infected annually; of these, 10 m will develop active disease. 2 million tb-related deaths worldwide every year.
