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HLTB21H3 Lecture Notes - Carboxymethyl Cellulose, Multiple Organ Dysfunction Syndrome, Circulatory Collapse

Health Studies
Course Code
Caroline Barakat

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Chapter 1 The Nature of Plagues
Peter Turner Legionnaires
- World War 2 veteran (65 years old)
- Summer of 1976
- Fell ill with high fever, chills, headache and muscle aches
- Few days later had a dry cough, chest pains, shortness of breath, vomiting and diarrhea
- Lungs filled with fluid and pus a few days later
- 221 people ill, 33 died
- Died from pneumonia which later turned into an outbreak called Legionnaires disease
- Aspiration of bacteria (called Legionella)
Mary Benton - TSS
- Suffering from overeating
- Pain every time she went to use the bathroom
- Had nausea, chills, diarrhea, and sore throat, and had a rash all over
- Died of multiorgan failure low blood pressure, hepatitis, renal insufficiency, and
internal blood clots
- Vaginal sample contained the bacterium staphylococcis aureus
- Had new disease TSS (toxic shock syndrome)
- Symptoms of disease
Each case began with vomiting and high fever, followed by lightheadedness and
fainting, the throat felt sore, and the muscles ached.
A day later, a sunburn-like rash appeared, and the eyes became bloodshot.
Within 3-4 days victims suffered confusion, fatigue, weakness, thirst and a rapid
pulse; the skin became cool and moist; and breathing became rapid.
This was followed by a sudden drop in blood pressure; if it remained low enough
for a long period, circulatory collapse produced shock
- TSS is a gender specific disease as it was linked to the use of certain types of tampons
(those containing cross-linked carboxymethyl cellulose with polyester foam)
SARS (Severe Acute Respiratory System)
- Started in February 2003
- Started with a 64 year old Chinese man who became ill with fever, dry cough, sore throat
and headache
- Suffered respiratory failure and died
- Those who came in contact with him during his illness had died days after him and it
- 2nd case was his brother in law who was in contact with him for only 10 hours, and died 3
days later
- 3rd case was a nurse who treated him; 4th was a businessman who stayed in the same hotel
- In 4 months there were over 8000 cases and 800 deaths
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