HLTB22H3 Lecture Notes - Lecture 6: Antibody, Chromosome, Interleukin 2

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Recall: hypersensitivity: set of undesirable reactions produced by the normal immune system including allergies and autoimmunity. Extreme physical sensitivity to particular substances or conditions: overreaction of immune system; is often damaging, type 1,2,3,4 hypersensitive reactions. Due to genetics: primary immunode ciency diseases: resulting from genetic or developing defect; are present from young age, secondary immunode ciency diseases: resulting from environmental cause; can develop at any age and are also called acquired immunode ciency diseases . Can happen at any age; may be caused by environmental reasons; can be acquired. Born and put into a plastic bubble and grew up in sterile environment. Couldn"t be given stem cell treatment as because no match of cells, even from own sister. Another cell transplant given to him had eventually killed him due to infection (probably from cancer: scid mice are immunode cient mice. Tuesday, october 25, 2016: can be carrier if both parents have it but aren"t being expressed.

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