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Lecture 7

Lecture 7 In-class Notes [Measles]

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University of Toronto Scarborough
Health Studies
Caroline Barakat

Lecture 7 - Measles Feb 24, 2010 Historical perspective - The origin of measles is unknown - Earliest description is attributed to Rhazes (900AD) - separated smallpox and measles clinically but thought they proceeded from the same cause - Prevailing theory was that the red rash represented the mothers menstrual blood that accumulates during the childs stay in the womb - Disease was welcomed - a way for the child to rid himself of the so called poision Modern history of Measles - Began in 1670, with Thomas Sydenhams (also known as father of clinical ovservation) description of his sons attack - He was the rst to clearly separate measles from smallpox, and he recognized complications such as cancrum oris (noma disease that leads to the destruction of tissue around the mouth) and encephalitis (inammation of the brain) - At the same time, scientists rejected the mothers blood theory - Francis Home (1757) demonstrated the infective nature of measles - succeeded in transmitting measles using blood from an infected child (810) Peter Ludwig Panum (1820 - 1885) - Sent by Danish govnt to investigate an epidemic of measles in the Faeroe Isles in 1846 - Geographic location ideal for an epidemiological study: 17 isolated islands - Situated between the Norwegian Sea and the NorthAtlantic Ocean, approximately halfway between Scotland
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