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HLTB21H3 (204)
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LEC 12.docx

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School
University of Toronto Scarborough
Department
Health Studies
Course
HLTB21H3
Professor
Caroline Barakat
Semester
Summer

Description
LEC 12 Beriberi – White rice plague 1616 – neurological disorder paralysis of hands and feet -kakke meaning leg disease --early 1900s – Eijkman established the disease is not germ-related -ex: polish rice to chicken became sick -1926, deficiency in vitamin B1 -thiamine -Germ Related to food being consumed - Scurvy – ‘explorers’ disease -gums grow over the teeth -early record date to 15 century -“plague of the sea” -mid 18 century, - disease was related to nutrition - low intake of lemon juice (James Lind first controlled clinical trial) th -19 century – outbreaks on land (Ireland, California, and New York) -led to identification and synthesis of vitamin C -vitamin c deficiency shuts down the synthesis of collagen Rickets -old disease – epidemic in England after 1650 th -late 19 century disease restricted to large industrial cities in Scotland, England and northern Europe -air quality linked (observation) -children in the fall more prone to disease (obse
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