NROB60H3 Lecture Notes - Lecture 4: Connexon, Fourth Ventricle, Basal Ganglia
6 Nov 2017
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Document Summary
The ups and downs of an action potential. The rst part, called the rising phase, is characterized by a rapid depolarization of the membrane. This change in membrane potential continues until vm reaches a peak value of about 40 mv. The apart of the action potential where the inside of the neuron is positively charged with respect to the outside is called the overshoot. The falling phase of the action potential is a rapid repolarization until the membrane is actually more negative than the resting potential. The last part of the falling phased is called the undershoot (after-hyperpolarization). o finally, there is a gradual restoration of the resting potential. The action potential lasts about 2 milliseconds (msecs). Intracellular recording : impaling the neuron or axon with a micro electrode - to measure the potential di btw the tip of the intracellular electrode and another placed in the solution. Optogenetics: foreign genes, membrane opens in response to light ex.
