PSYB65H3 Lecture Notes - Lecture 7: Codine, Cyclic Adenosine Monophosphate, Depressant

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Published on 17 Apr 2013
School
UTSC
Department
Psychology
Course
PSYB65H3
Professor
Lecture 7 PSYB65
Drug any chemical you can use and ingest, very specific
classes of drugs
Types:
o Prescription drugs
o Over the counter drugs from drugstore without
prescription (Codine -canada)
o Social drugs nicotine, caffeine, alcohol
o Can go out and buy these, not produced for their
psychoactive effect (glue)
o Cant go out and buy these (marijuana)
Tolerance
o Concept that if a drug is taken repeatedly most drugs
shows decreasing behavioral effect
o Mechanism - if you have drugs that alter a system,
postsynaptic side compensates by reducing number or
sensitivity of receptors
o Ex. Depressant slows down system, system will
compensate by increasing sensitivity and number of
receptors
Withdrawal
o If you’ve been taking drug for a long period of time,
then suddenly stop, you have a craving for it
o Behavioural effect is opposite of effect of drug itself
Stimulant compensated with lesser
receptors….withdrawal=stimulant is gone…pre-
synaptic axon is now putting out regular amount
of transmitter…only one receptor though? No
effect on postsynaptic cell because sensitivity is
too low…persons activity levels are really
down/understimulated
o If someone is on stimulants and go through withdrawal,
they’ll be tired, lethargic, sad –not life threatening
o Depressants on withdrawal, brain is hyperexcitable,
can cause seizures, agitation can cause death
(alcohol)
Addiction
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