PSYB65H3 Lecture Notes - Lecture 3: Dementia, Encephalitis, Multiple Sclerosis

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Published on 17 Apr 2013
School
UTSC
Department
Psychology
Course
PSYB65H3
Professor
Lecture 3
Vascular(blood) supply brain:
What can go wrong?
1. Blockage of vascular supply/blood flow
o Diff kinds of blockages
Cerebral vascular accident (CVA): also used to
refer to a stroke, severe interruption of blood
supply to brain. When this happens, results in
ischemia (brain not receiving enough oxygen and
glucose---infarct)…can happen fast(almost
always) or slowly
Encephomalacia blood supply loss is very
slow, brain tissue softens/deteriorates, caused by
slow blockages, associated with elderly (cause of
some dementia)
TIA (transient ischemic attack) temporarily,
short lived, not enough oxygen going to brain,
most often seen in migraines, constriction of
muscles surrounding the blood vessels, mostly
affects vision
o What causes blockages?
Thrombosis locally formed blockage, blood
clots, when you get old people have problems
with blood becoming thicker, more likely to form
clots (sedentary)
Embolism blockage formed elsewhere in
body, breaks off and floats around arteries and
then lodges in the brain (most common break off
from the leg, travels through vascular supply,
lodges in brain causes CVA…or plaque
blockages caused by cholesterol (arteriolosis)
2. Vessel Bursting:
1. Cerebral Hemorrhage (Massive
bleeding) Blood vessels burst,
massive bleeding inside the brain,Can be
fatal, depends on which artery it affects,
kills brain tissue
2. Subdoral Hematoma bleeding
outside the brain, between dora and
brain, no bleeding inside brain, puts
great deal of pressure on the brain,
squeezes cerebral spinal fluid from one
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Document Summary

Blockage of vascular supply/blood flow: diff kinds of blockages. Cerebral vascular accident (cva): also used to refer to a stroke, severe interruption of blood supply to brain. When this happens, results in ischemia (brain not receiving enough oxygen and glucose---infarct) can happen fast(almost always) or slowly. Encephomalacia blood supply loss is very slow, brain tissue softens/deteriorates, caused by slow blockages, associated with elderly (cause of some dementia) Thrombosis locally formed blockage, blood clots, when you get old people have problems with blood becoming thicker, more likely to form clots (sedentary) Encephalitis some sort of infection of the brain: viral infections polio, rabies, herpes, bacterial (most common: meningitis) xi. Fungal infection extremely rare, in advanced cases of untreated aids xii. Parasitic infections rare in developed countries, malaria, amoebic. Gliul (helper cells) outnumber neurons, 10 for every neuron. Myelin sheath wraps around axon, to make process faster(oligodendrocyte cell) Disease of the cells destroys glial cells myeline.

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