PSYB65H3 Lecture Notes - Lecture 4: Reuptake, Spasms, Generalised Tonic-Clonic Seizure

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Neuron dendrites => cell body => axon => terminal buttons. When stimulated, they open and allow sodium into the cell (sodium is positively charged) The inside of the cell becomes more positive, and if enough sodium goes in, the cell reaches a threshold. ==> all the pores open up, makes the cell extremely positive. This spike is known as an action potential. => starts in the cell body, zips down to axon. => goes down to the synapse (gap between terminal buttons and the next cell"s dendrite: synaptic vesicles carry transmitter substances, when the action potential reaches the end of the axon, vesicles open up and stimulate the next dendrite. Receptors on the axon side are known as pre-synaptic. Receptors on the dendrite side are known as post-synaptic. How to intervene: dopamine has to be synthesized, transmitters have to be stored (packaged or will be destroyed) * some chemicals keep them from being packaged: release, receptor activation.

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