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lect 8

Course Code
Ted Petit

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Drugs and the Brain
1. Prescribed
2. Over the counter
3. Social Drug
4. Drugs not produced commercially(weed) or drugs producted
commercially but not for psychoactive effect (glue)
Tolerance: a decrease in behavioural affect if taken repeatedly
- every drug has a different level
How tolerance works in stimulants:
Stimulants cause an increase in neurotransmitters which increases the
stimulation of receptors. Because receptors are bombarded they adjust by
decreasing the amount of receptor sites to compensate for over activation.
Therefore it will not fire as often because over time it is regulated and you
get a dampening effect
Tolerance in Depressants:
Depressants cause a decrease in activation of post-synaptic cells and
therefore will adjust to have more receptor(sensitivity) to compensate for
under activation resulting in less relaxation of brain
Withdrawl: The opposite of high effect; (-) psyc and physical symptoms
Withdrawl in stimulants:
After so much of the drug, the brain has now regulated it self to having
decreased sensitivity/ receptors. When normal amounts of begin again (drug
is stopped) the post-synaptic cell is under stimulated (less activity)
Stimulationdepression (for this reason someone can be take off right
Withdrawl in Depressant:
Excess receptors cause brain to be over stimulated when normal levels begin.
This results in opposite effect of high
DepressantStimulation (CANNOT take off right away; siezures)
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