PSYB65H3 Lecture : Lecture6.docx

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Exam: 5-7pm/ 50questions, 25 on the lecture material, 25from the textbook all multiple choice. Today"s lecture will be on the exam, no pictures on the exam. There will be details to distinguish between the a and the a+ students. Delusions: just thinking that people are plotting against you. If you make it to 30 then you"re good to go! Phenothiazines and chlor promazine which block sites for the biogenic amines. The drugs that were most effective were blockers for dopamine. People who take dopamine stimulants(amphetamine) will show schizophrenic symptoms (they will have delusions, hallucinations), so it become very clear that over stimulation of dopaminergic receptors caused schizophrenic symptoms and if they were reduced then schizophrenic patients were better. If you look at the number of dopamine receptors they have 6times as many(the. D2 and d4 receptors) and therefore some gene is obviously coding for dopamine receptors and something is wrong with this gene and this causes schizophrenia.

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