PSYB65H3 Lecture 8: Psyb65 lecture 8.docx
Document Summary
Schizophrenia: hallucinations and delusions verbal hallucinations hear people talking to them, delusions can be paranoid think someone"s out to get them. Problem is transmitter; not psychological: occurs in 1/100 people about 1% of population. Look at direct family (parent, children) you will find that the rate of schizophrenia goes up to 10-15% depending. Genetic component to the disorder: twin studies. If the twins are dizygotic, then the incidence that one is schizophrenic. The probability that the other will get it is about the same, 10-15% Strictly related to dopamine blockers most effective. Something about dopamine receptor blockers *reduce symptoms) Dopamine stimulants- such as amphetamine, if you were a schizophrenic but no symptoms, you immediately became psychotic: even in normal individuals, they will begin to show schizophrenic behaviours. Have to give them in high dosage for 24 hours: started looking at the brains of schizophrenics. They had normal levels of dopamine had too many dopamine receptors.
