PSYB65H3 Lecture : lecture notes 07 - drugs(1)
Document Summary
Prescription drugs, otc drugs, social drugs (e. g. cocaine), other tolerance most drugs lead to decreasing behavioural effect when taking drug repeatedly. Taking drugs repeatedly causes more and more neurotransmitter release. More and more transmitter release to postsynaptic cell, hyperstimulate receptor s. Cell reduce receptors to compasate this overactivition, not fire as often (decr ease sensitivity) withdrawal. When stimulus(drugs) is absent, transmitter release back to normal, but now the re are fewer receptors -> understimulate. Back to narmal for a while due to neuron"s flexibility. Withdrawal from depressant can be severe enough to be life threatening addiction: people want to take drugs. Phisical dependence of drug (will cause phisical symptoms that can be measured/ observed when withdrawal) More rapid effect, more addiction e. g. cocaine: more concentrated -> more rapid effect -> more addictive addicting drugs caffeine-- Shift cortical eeg to arousal state and inhibit sleep (most stimulants do this) Withdrawal effect: headaches (caffeine helps reduce headache), digestive system slow down.
